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New heart drug works better than current treatment, study finds

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In a huge international study, an experimental drug for heart failure worked significantly better than the current backbone of treatment, paving the way for the biggest therapeutic advance in decades.

Novartis’ twice-a-day pill, still known by its code name LCZ696, reduced deaths, hospitalizations, and disabling symptoms of heart failure. It also had fewer serious side effects than the standard therapy, a blood-pressure-lowering medication called enalapril.

“We designed this study to try to change the cornerstone of treatment — to replace…

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