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Mariners pitcher Anthony Misiewicz is seen in the dugout after being taken out in the eighth inning, when he allowed three runs to score by the Baltimore Orioles. Ken Lambert / The Seattle Times

When a team is forced into making a “bullpen start,” the suboptimal situation rarely yields ideal results even with a bullpen that has been outstanding leading up to the game.

Why?

Well, in a bullpen start, you are asking a collection of relievers, usually four to five, to all pitch well in the same game. The gods of baseball regression just don’t seem to let that happen regardless of recent outings.

But the Mariners’ bullpen, which has unexpectedly produced the lowest earned run average in Major League Baseball – 2.30 coming into the game Monday, seemed like it might produce a gem while filling in for injured ace Marco Gonzales.

For seven innings, Seattle paraded out reliever after reliever, each holding the Baltimore Orioles scoreless.

But that run ended when one of their best relievers this season was finally scored upon. Left-hander Anthony Misiewicz, who hadn’t allowed an earned run in 12 appearances and 9 2/3 innings pitched, couldn’t protect a one-run lead.

Misiewicz gave up three runs in what ended up being a decisive five-run eighth inning and an eventual 5-3 victory for the Orioles.

Seattle manager Scott Servais used five relievers to hold the Orioles scoreless over the first seven innings.

Erik Swanson: two innings, three strikeouts

Domingo Tapia: one inning, two hits, a walk and a strikeout

Will Vest: 1 2/3 innings, two hits allowed

Drew Steckenrider: 1 1/3 innings, two strikeouts

Keynan Middleton: one inning, one strikeout

When he went to Misiewicz, one of his best set-up relievers, he expected much of the same.

“You never know what’s going to happen in a bullpen game,” Servais said. “Certainly tonight, we used like seven different pitchers and like I’ve often said when you use that many, it’s hard for them all to be perfect when you go out there.”

Tom Murphy, who was tasked with catching all those different pitchers with various velocities, styles and pitch movements, gave the Mariners their first and only lead in what was a scoreless game for the first 4½ innings.

With one out in the bottom of the fifth inning, Murphy worked a 3-2 count and then stayed on a 93-mph fastball away from Orioles’ starter Dean Kremer. One of the strongest players on the team, or any team, Murphy muscled the ball over the wall in right center for his third homer of the season.

The solo shot gave Seattle a 1-0 lead.

Misiewicz entered in an optimal situation where he would face No. 9 hitter Pat Valaika, who was hitting .125 and then have a lefty vs. lefty matchup against Baltimore’s best hitter – Cedric Mullins.

But Misiewicz didn’t quite have his typical command. He walked Valaika and then left a cutter to Mullins up in the strike zone and out over the plate — perhaps more than he wanted. Mullins hit a deep fly ball that right fielder Mitch Haniger was tracking off the bat. Sensing the wall was near, Haniger leapt high for the ball, extending his glove and crashing into the wall. As he landed on his back on the warning track, it seemed for a moment like Haniger might pull the ball from his glove to signal an amazing catch.

But he didn’t have it.

Replays showed the ball, hitting right off the top of his glove and going over the wall. He missed a spectacular, perhaps game-saving catch, by about an inch or two.

The Orioles had a 2-1 lead and they weren’t finished.

Austin Hays followed with a double and advanced to third on Trey Mancini’s deep fly ball to right field. That was the only out Misiewicz would get in the outing. He was replaced by rookie Wyatt Mills, who made his MLB debut Friday.

“Miz hasn’t been scored upon all year, but he was not quite as sharp as he normally is,” Servais said. “We’ve been using him a lot lately. When you go into a game like this, you try to map it out and we were in a pretty good spot.”

Miseiwicz wouldn’t allow his usage or workload to serve as an excuse.

“I don’t think that was it at all,” he said. ” I know I’m out there a lot, but it’s my job. When my number gets called, I’ve got to be able to perform to the best of my ability and tonight I had an off day. Unfortunately, it was one off day too many.”

With the Mariners’ infield playing on the grass, Maikel Franco hit a ground ball that shortstop J.P. Crawford gloved but couldn’t get a decent throw to home, instead settling for an out at first.

Mills couldn’t keep the deficit to two runs. He walked a batter and then gave up a two-run homer to Freddy Galvis that made it 5-1.

That homer loomed large when Haniger sent a ball into the visitors’ bullpen for a two-run homer in the bottom of the eighth. Haniger’s eighth homer of the season made it 5-3.